RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
Gas5
RNA ID
RNA Type
lncrna
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
RT-PCR;
Target
NA
Pathway
PI3K-AKT SIGNALING PATHWAY
PubMed ID
Title
Overexpression of lncRNA GAS5 attenuates cardiac fibrosis through regulating PTEN/MMP-2 signal pathway in mice
Year
2019
Function
"Overexpression of gas5 after injection with PCDNA-gas5 could attenuate cardiac fibrosis and improve cardiac function through increasing the expression of PTEN and decreasing the expression of MMP-2, alfa-SMA, and collagen i."